Monday, Oct. 18, 2004

BAD BLOOD

By Sora Song

For patients with acute heart problems, a blood transfusion--an increasingly common procedure--can double the risk of death and triple the risk of another heart attack within a month, according to a study in the Journal of the American Medical Association. Doctors at Duke Clinical Research Institute analyzed data from three big trials involving more than 24,000 patients, 10% of whom had had transfusions during their first 30 days in the hospital. Researchers speculate that transfused blood may lack nitric oxide--essential for delivering oxygen to tissues--and cause harmful inflammation. Transfusions can't be halted, says the study's lead author, but cardiologists can be more selective about who gets them.--By Sora Song